Headline Dec 31, 2014/

''' BLOOD *SUPPORTS* LIFE '''

FOR A NOBEL LAUREATE,  the molecular biologist Max Perutz made a lot of mistakes. His science was strewn with assertions that were not supported by the sparse evidence he had gathered. No matter.

He was eventually right about the important things   -and gentleman enough to concede his errors.

With bloody-minded persistence, Perutz mastered the painstaking task of analysing images of haemoglobin,  the component of blood that carries oxygen. This was no mean feat:

A haemoglobin consists of thousands of atoms and,  at the time, only simple structures of tens of atoms had been mapped. It was for this work that Perutz was awarded the Nobel prize in chemistry in 1962.

But his triumphal announcement of the correct structure of haemoglobin was by no means his first solution to the problem: he had previously claimed all sorts of unlikely arrangements, backing down each time a colleague spotted a fatal flaw.

Even when he did finally hold the secret to why blood supports life, he did not piece together the evidence to produce the ultimate result. Indeed, Perutz was furious when a junior researcher saw:

 How the final piece fitted and could not resist popping it into its slot, completing what Perutz viewed as his jigsaw puzzle. 

Nevertheless, it was Perutz who had gathered all the pieces and who ensured, in the end, that they were correctly assembled.

Perutz was long the outsider. Of Jewish descent, he was a lapsed Catholic by religion. He left his native Austria in  1936, two years before Hitler annexed it. The outbreak of war saw him expelled to Canada as an enemy alien.

On returning to Cambridge, he was not welcomed by his colleagues. It was only after he won the Nobel prize that he felt accepted as an Englishman, despite being naturalised as a British subject 20 years earlier.

As a scientist, too, Perutz was always on the fringe. His field of endeavour, x-ray crystallography, was neither physics nor maths nor chemistry nor biology but a combination of these.

As often happens to researchers working on interdisciplinary areas of science, his progress was impeded by an establishment that sought to promote existing subjects. He lived from grant to grant, each lasting a matter of moths.

Nevertheless, he managed to establish the unit in which James Watson and Francis Crick elucidated the double helix structure of DNA.

A decade later a whole institute was established under him 

Georgina Ferry's biography captures not only the scientific advances made by Perutz but also his curious personal qualities.

A skinny, sickly, and, for much of his life, skint individual,  Perutz is an unlikely hero. 

He was demanding   -his diet required him to to eat black bananas, even in February  -and he was unselfconscious in ensuring that his elaborate needs were met.  

He was also naive in insisting that scientific reasoning would trump political thought and religious teaching. 

Ms Ferry portrays his foibles sympathetically. Perutz used to complain that, although he was famous, few  people knew what it was he had achieved. 

By combining scientific with personal anecdotes, her book goes a good way towards addressing that balance.

With respectful dedication to the Students, Professors and Teachers of the world. See Ya all on  !WOW!   -the World Students Society Computers-Internet-Wireless: 

''' Science Honours '''

'''Good Night and God Bless

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